Valve setup for SMB chromatography

A method for assembling a valve setup, the method comprising:

• providing a valve cassette block comprising a plurality of valves which are controllable via a control surface of the valve cassette block;
• providing a valve control block having an operation surface, the valve control block being configured to control each of the plurality of valves when the operation surface is in close contact with the control surface of the valve cassette block in an operation position, the valve control block comprising at least one second positioning component and a pair of hinge arms;
• providing at least one swiveling door hinged to the valve control block such that an open state of the swiveling door allows arranging the valve cassette block into the operation position with its control surface arranged at the operation surface of the valve control block, while a closed position of the swiveling door is configured to hold the valve cassette block in the operation position with an inner surface of the swiveling door abutting a rear surface of the valve cassette block opposite to its control surface;
• providing at least one flexible pressurizing tube arranged at the inner surface of the swiveling door such that the pressurizing tube presses against the rear surface of the valve cassette block, when the pressure in the pressurizing tube is increased;
• in the open state of the at least one swiveling door, mounting the valve cassette block in the operation position;
• locking the at least one swiveling door in the closed state, with the valve cassette block in the operation position;
• and
• pressurizing the at least one pressurizing tube such that it presses against the rear surface of the valve cassette block, thereby pushing the valve cassette block with its control surface against the operation surface of the valve control block.