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US 11,873,272 B2Granted
Antimicrobial and antiviral sulfur containing glycerol monoester derivatives
AssigneeNiche Biopharmaceuticals LLC
InventorsDayton T. Reardan, Paul Brennan, Patrick Schlievert
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Abstract
The disclosure relates generally novel sulfur containing glycerol mono-ester derivatives and methods useful for treating gram positive, gram negative, fungal and envelope viral infections in a patient.
Claims20
A compound of Formula (I),
- wherein:
- R1 is selected from the group consisting of alkyl, alkenyl, and alkynyl;
- R2 and R3 are independently selected from the group consisting of hydrogen, COR4, —CON(H)R4, —CO2R4, or P(O)(OR4)2;
- or, taken together with the carbon to which they are attached, R2 and R3 may form a 3- to 5-membered aliphatic carbocyclic ring;
- R4 is H, alkyl, alkenyl, aryl, cycloalkyl, heterocyclyl, or heteroaryl;
- and
- X is S;
- or a pharmaceutically acceptable salt thereof.
5 more elements
Dependencies are inferred from the claim text.