Plant virus movement proteins and methods of using same
AssigneeMolecular Transfer, Inc.
InventorsGulilat Gebeyehu, Joel Jessee
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Abstract
Disclosed herein are transfection complexes comprising at least one cell surface ligand; at least one helper lipid component; and a transfection enhancer. Also disclosed are pharmaceutical compositions comprising the disclosed transfection complexes, and a pharmaceutically acceptable carrier. Further, disclosed are methods of transfecting a cell, the method comprising the steps of: obtaining a transfection complex as disclosed; and contacting a cell with the transfection complex.
Claims15
A transfection complex for transfection of a eukaryotic cell comprising a transfection agent and a peptide sequence selected from SEQ ID NOs:
- 540-547, 549, 551, 552, 559-564, 566, and 568-571 optionally linked to a nucleic acid binding moiety, wherein the transfection agent is a lipoplex or lipid aggregate comprising at least one piperazine based cationic lipid.
Dependencies are inferred from the claim text.