Method and system for dissociating biological tissue into single cells using ultrasonic energy
AssigneeMicrosonic Systems Inc.
InventorsVibhu Vivek, Poonam Sansanwal
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Abstract
A method of dissociating single cells from a biological tissue sample is described herein, along with systems for performing such methods. The method includes generating one or more ultrasonic wave pulses using a transducer comprising one or more Fresnel Annular Sector Actuator (FASA) elements; and applying energy from the generated one or more ultrasonic wave pulses to a sample container holding the biological tissue sample through a coupling medium that couples the one or more FASA elements to the sample container to dissociate single cells from the biological tissue is described herein.
Claims29
A method of dissociating single cells from a biological tissue sample, comprising:
- generating one or more ultrasonic wave pulses using a transducer comprising one or more Fresnel Annular Sector Actuator (FASA) elements;
- and
- applying energy from the one or more generated ultrasonic wave pulses to a biological tissue sample contained by a sample container through a coupling medium that couples the one or more FASA elements to the sample container to dissociate single cells from the biological tissue.
A system for dissociating single cells from a biological tissue sample, comprising:
- a transducer comprising one or more Fresnel Annular Sector Actuator (FASA) elements configured to generate one or more ultrasonic wave pulses;
- a sample container configured to hold the biological tissue sample;
- and
- a coupling medium configured to couple the one or more FASA elements to the sample container and transmit energy from the plurality of ultrasonic wave pulses generated by the transducer to the sample container to dissociate single cells from the biological tissue sample.
Dependencies are inferred from the claim text.