Bicyclic compounds

A compound of Formula (IVa) or Formula (IVb), or a pharmaceutically acceptable salt or a pharmaceutically acceptable solvate thereof:

• wherein,
• RX is independently hydrogen, halogen, nitro, oxo, thioxo, imino, oximo, —OR3, —SR3, —CN, —C(═O)R2, —S(═O)R3, —S(═O)2R3, —N(R3)2, —NR3S(═O)2R3, —NR3C(═O)R3, —NR3C(═O)OR3, substituted or unsubstituted C1-C6 alkyl, substituted or unsubstituted C1-C6haloalkyl, substituted or unsubstituted C2-C4alkenyl, substituted or unsubstituted C2-C4alkynyl, substituted or unsubstituted C1-C6heteroalkyl, substituted or unsubstituted C3-C10cycloalkyl, substituted or unsubstituted C2-C10heterocycloalkyl, substituted or unsubstituted aralkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• each R2 is independently —CN, —OR3, —SR3, —S(═O)2R3, —N(R3)2, —C(═O)OR3, —N3, F, substituted or unsubstituted C1-C6alkyl, substituted or unsubstituted C1-C6haloalkyl, substituted or unsubstituted C1-C6heteroalkyl, substituted or unsubstituted C3-C10cycloalkyl, substituted or unsubstituted C2-C10heterocycloalkyl, substituted or unsubstituted aralkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• each R3 is independently hydrogen, substituted or unsubstituted C1-C6alkyl, substituted or unsubstituted C1-C6haloalkyl, substituted or unsubstituted C1-C6heteroalkyl, substituted or unsubstituted C3-C10cycloalkyl, substituted or unsubstituted C2-C10heterocycloalkyl, substituted or unsubstituted aralkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R5 is F, —SF5, substituted C1-C6alkyl, substituted or unsubstituted C1-C6haloalkyl, substituted C1-C6alkyloxy, or substituted C1-C6alkylthio;
• and
• n is 0, 1, 2, 3, or 4.