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US 11,866,416 B2Granted
Streptococcus mutans glucosyl transferase inhibitors for dental caries therapy
AssigneeThe UAB Research Foundation
InventorsSadanandan E. Velu, Hui Wu, Qiong Zhang, Bhavitavya Nijampatnam
Life of this patent
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Abstract
The present invention is related to the inhibition of the formation of Streptococci biofilms through the inhibition of glucosyl transferase (Gtf). Compounds, compositions and methods for inhibiting Streptococcus biofilm formation, as well as for preventing, inhibiting and/or treating the formation of dental caries, and methods of identifying compounds that prevent, inhibit and/or treat the formation of dental caries are provided.
Claims20
A compound selected from the group consisting of:
A compound selected from the group consisting of:
Dependencies are inferred from the claim text.