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US 11,865,475 B2Granted
Acoustically settled liquid-liquid sample purification system and method of use
AssigneeLife Technologies Corporation
InventorsScott P. Collins, Christopher D. Brau, Nephi D. Jones
Life of this patent
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Abstract
A sample purification system includes a mixing zone; a settling zone in fluid communication with the mixing zone; a mixer element disposed in the mixing zone, the mixer element being configured to mix immiscible liquids to form a mixture; and a first acoustic wave settler configured to emit an acoustic wave into the mixture.
Claims8
A method of purifying a sample in a two-phase system, the method comprising:
- mixing a first liquid with a second liquid to form a first mixture, the first liquid comprising a first liquid phase, the second liquid comprising a second liquid phase, the second liquid being immiscible in the first liquid, the first mixture comprising a portion of the second liquid dispersed in the first liquid;
- settling a first portion of the first mixture;
- and
- applying an acoustic wave to the settled first portion of the first mixture to form a first acoustically settled mixture;
- wherein the step of applying the acoustic wave occurs in an acoustic settling loop, the acoustic settling loop having a first end in fluid communication with a settling zone and a second end in fluid communication with the settling zone.
2 more elements
Dependencies are inferred from the claim text.