Compositions and methods for treatment of uremic cardiomyopathy
AssigneeMarshall University Research Corporation
InventorsZijian Xie, Joseph I. Shapiro, Jiang Liu
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Abstract
Methods for treating uremic cardiomyopathy are provided and include the step of administering a polypeptide antagonist of a Na/K ATPase/Src receptor complex to a subject in need thereof. The polypeptide anatagonist can further include a cell penetrating polypeptide. Methods of treating anemia, including anemia-associated with chronic kidney disease, are also provided.
Claims5
A method for treating anemia, comprising administering a polypeptide antagonist of a Na/K ATPase/Src receptor complex to a subject in need thereof, wherein the polypeptide anatagonist comprises the sequence of SEQ ID NO:
- 1 or a functional fragment thereof, and wherein the anemia is chronic kidney disease-induced anemia.
Dependencies are inferred from the claim text.