Prophylactic and nutraceutical therapy

A method for preventing formation of a colon cancer, wherein the method comprises administering to an individual that does not have colon cancer a biologically active complex comprising alpha-lactalbumin or a variant thereof or a peptide of up to 50 amino acids comprising SEQ ID NO:

• 3 or 5 and a fatty acid or a salt thereof, wherein:
• i) the alpha-lactalbumin is human alpha-lactalbumin and the biologically active complex is HAMLET;
• or
• ii) the alpha-lactalbumin is bovine alpha-lactalbumin and the biologically active complex is BAMLET;
• and
• iii) the variant is a variant of native mature alpha-lactalbumin wherein all of the cysteines have been mutated to other amino acids.

A method for preventing formation of colon cancer, wherein the method comprises administering to an individual that does not have colon cancer a biologically active complex comprising:

• i) alpha-lactalbumin;
• or
• ii) a variant of alpha-lactalbumin, wherein the variant comprises an alpha domain and has at least 80% sequence identity to alpha-lactalbumin;
• and
• iii) a fatty acid or a salt thereof.