Polypeptides useful for detecting anti-rhabdovirus antibodies

A polypeptide comprising

• an ectodomain of a rhabdovirus glycoprotein, and
• a heterologous multimerization domain linked to the ectodomain,
• wherein the ectodomain is an ectodomain of a SF-rhabdovirus glycoprotein having
• at amino acid position 306 an amino acid residue other than an arginine residue, and/or
• at amino acid position 303 an amino acid residue other than an arginine residue, and/or
• at amino acid position 305 an amino acid residue other than a basic amino acid residue, and/or
• at amino acid position 307 an amino acid residue selected from the group consisting of lysine residue, leucine residue, isoleucine residue, valine residue and tryptophane residue, and/or
• at amino acid position 308 a lysine residue,
• and having
• at amino acid position 333 an amino acid residue other than an arginine residue, and/or
• at amino acid position 330 an amino acid residue other than an arginine residue, and/or
• at amino acid position 332 an amino acid residue other than a basic amino acid residue, and/or
• at amino acid position 334 an amino acid residue selected from the group consisting of lysine residue, leucine residue, isoleucine residue, valine residue and tryptophane residue, and/or
• at amino acid position 335 a lysine residue,
• and wherein the numbering of the amino acid positions refers to the amino acid sequence of wild type SF-rhabdovirus glycoprotein as set forth in SEQ ID NO:16,
• and wherein the heterologous multimerization domain comprises or consists of a IgG Fc domain.