Method for treating breast cancer
AssigneeImam Abdulrahman Bin Faisal University
InventorsB. Rabindran Jermy, Vijaya Ravinayagam, Dana Almohazey
Life of this patent
Estimating the term…
Abstract
A nanomedicinal composition comprising a nanocarrier and a pharmaceutical agent mixture comprising an anti-cancer therapeutic and an antioxidant. The nanocarrier comprises a porous silicate matrix and particles of a magnetic ferrite disposed in the pores of the porous silicate matrix. The pharmaceutical agent mixture is disposed in the pores and/or on the surface of the nanocarrier by a solution phase impregnation process. The nanomedicinal composition is used in a method of treating breast cancer.
Claims10
A method for treating a breast cancer in a subject in need of therapy, comprising:
- administering to the subject a pharmaceutical composition comprising a nanomedicinal composition,
- wherein the nanomedicinal composition comprises:
- a nanocarrier comprising:
- mesosilicalite;
- and
- particles of a magnetic ferrite of formula MFe2O4 disposed in the pores of the mesosilicalite, where M is Cu;
- and
- a pharmaceutical agent mixture comprising cisplatin and curcumin disposed in the pores and/or on a surface of the nanocarrier;
- wherein the nanocarrier has a BET surface area of 70 m2/g and an average pore volume of 0.1 cm3/u,
- wherein the nanomedicinal composition releases 88% of the cisplatin and 40-50% of the curcumin over 72 hours in a solution with a pH of 5.6.
Dependencies are inferred from the claim text.