Systems and methods for regioselective carbonylation of 2,2-disubstituted epoxides for the production of alpha,alpha-disubstituted beta-lactones
AssigneeCornell University
InventorsGeoffrey W. Coates, Jessica Rachel Lamb, Kristine Klimovica, Aran Kathleen Hubbell
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Abstract
Provided are methods of producing carbonyl compounds (e.g., carbonyl containing compounds) and catalysts for producing carbonyl compounds. Also provided are methods of making polymers from carbonyl compounds and polymers formed from carbonyl compounds. A method may produce carbonyl compounds, such as, for example α,α-disubstituted carbonyl compounds (e.g., α,α-disubstituted β-lactones). The polymers may be produced from α,α-disubstituted β-lactones, which may be produced by a method described herein.
Claims13
A method of producing an α,α-disubstituted carbonyl compound comprising:
- providing a reaction mixture comprising a 2,2-disubstituted epoxide and a catalyst;
- and
- contacting the reaction mixture with carbon monoxide,
- wherein the α,α-disubstituted carbonyl compound is produced and the α,α-disubstituted carbonyl compound is the major carbonyl compound product.
Dependencies are inferred from the claim text.