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US 11,850,729 B2Granted
System and method for automated experimentation
AssigneeSpaero Inc.
InventorMitchell Adler
Life of this patent
Estimating the term…
Abstract
In variants, a method for automated experimentation can include: determining experimental constraints, constructing a computational representation of the experiment, optimizing the computational representation subject to the experimental constraints, determining instructions for a laboratory robot based on the optimized computational representation, and/or any other suitable steps.
Claims12
A system, comprising:
- a user interface configured to receive experiment constraints;
- a processor configured to:
- determine an initial graphical computational representation of the experiment based on the experiment constraints;
- optimize the initial graphical computational representation to determine an optimized graphical computational representation comprising a set of nodes connected by a set of edges, wherein each edge is associated with an experiment operation, wherein each node is associated with a composition for a sample;
- and
- determine software instructions based on the optimized graphical computational representation;
- a container carrier comprising physical containers, wherein each node is mapped to a physical container on the container carrier;
- and
- a liquid-handling robot system configured to execute the software instructions, wherein the executing the software instructions comprises, for each node:
- manufacturing the associated sample with a composition matching the associated sample composition, wherein the associated sample is located within the respective physical container.
7 more elements
A system, comprising:
- a user interface configured to receive experiment constraints;
- a processor configured to:
- determine an initial graphical computational representation of the experiment based on the experiment constraints;
- optimize the initial graphical computational representation to determine an optimized graphical computational representation comprising a set of nodes connected by a set of edges, wherein each edge is associated with an experiment operation, and wherein each node is associated with a composition for a sample, wherein the optimized graphical computational representation comprises a directed acyclic graph, wherein each composition comprises a concentration and a volume, wherein optimizing the initial graphical computational representation comprises determining the concentration and volume associated with each node of the optimized graphical computational representation;
- and
- determine software instructions based on the optimized graphical computational representation;
- a container carrier comprising physical containers, wherein each node is mapped to a physical container housing the sample associated with the node;
- and
- a liquid-handling robot system configured to execute the software instructions.
6 more elements
A system, comprising:
- a user interface configured to receive experiment constraints;
- a processor configured to:
- determine an initial graphical computational representation of the experiment based on the experiment constraints;
- optimize the initial graphical computational representation to determine an optimized graphical computational representation comprising a set of nodes connected by a set of edges, wherein each edge is associated with an experiment operation, wherein each node is associated with a composition for a sample, wherein each experiment operation is associated with an aspiration error, wherein optimizing the initial graphical computational representation comprises minimizing an aggregate aspiration error;
- and
- determine software instructions based on the optimized graphical computational representation;
- a container carrier comprising physical containers, wherein each node is mapped to a physical container housing the sample associated with the node;
- and
- a liquid-handling robot system configured to execute the software instructions.
6 more elements
Dependencies are inferred from the claim text.