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US 11,850,334 B2Granted
Immobilised biological entities
AssigneeCarmeda AB
InventorsDagmar Pikas, Johan Riesenfeld, Karin Leontein, Eva Koch, Stefan Oscarson
Life of this patent
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Abstract
There is provided inter alia an anticoagulant surface which surface has covalently bound thereto a plurality of fragments of heparin, wherein said fragments consist of 5-18 saccharide units and at least some of said plurality of fragments comprise polysaccharide sequence A, which surface catalyses the inhibition of FIIa and FXa by AT.
Claims32
An anticoagulant surface which surface has covalently bound thereto a plurality of fragments of heparin, wherein said fragments consist of 5-18 saccharide units and at least some of said plurality of fragments comprise polysaccharide sequence A:
- wherein R=Ac or SO3−
- which surf ace catalyses the inhibition of FIIa and FXa by AT, and wherein the surface has a heparin fragment concentration of at least 1 μg/cm2.
Dependencies are inferred from the claim text.