Bioprinted hair follicles and uses thereof
AssigneeOrganovo, Inc.
InventorsEmily Bozek, Jonah Cool, Harry S. Rapoport, Christian Holmes, Stephen L. Pentoney, Chad Viergever, Howard Hwang, Christopher Shaw
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Abstract
Disclosed are compositions comprising cellular constructs comprising mesenchymal cells and epithelial cells. Also disclosed are methods of making the cellular constructs, methods of hair restoration, and kits. The invention also discloses parallel bio-printing systems and methods for making cellular constructs, such as cellular constructs comprising mesenchymal cells and epithelial cells.
Claims23
A composition comprising a hydrogel comprising a plurality of channels comprising removable cellular constructs that comprise cysts capable of growing hair, wherein each cellular construct is in the form of a column comprising mesenchymal cells and epithelial cells, and wherein the mesenchymal cells comprise dermal papilla cells and the epithelial cells comprise keratinocytes.
Dependencies are inferred from the claim text.