Mixing vial

A syringe system, the system comprising:

• a syringe with an axially movable plunger having a distal end defining a shoulder;
• and
• a mixing vial comprising:
• a vessel, the vessel comprising a hollow interior chamber having a proximal end and an open distal end;
• a stopper including an open first end, a closed second end opposite and spaced apart from the open first end, and at least one stopper side wall extending from the open first end to the closed second end, wherein a hollow interior chamber is defined by the at least one stopper side wall and the closed second end, the stopper being positioned in a sealing relationship with a portion of an inner surface of the hollow interior chamber of the vessel, wherein an outer surface of the at least one stopper side wall includes two ribs extending radially outwardly from the at least one stopper side wall, wherein each of the two ribs are axially spaced apart from each other, wherein an inner surface of the at least one stopper side wall defines an annular groove, wherein the groove is located axially between two adjacent ribs of the two ribs;
• and
• a dislodgeable plug disposed within the hollow interior chamber of the stopper such that at least a portion of an edge of the dislodgeable plug is disposed within the groove of the stopper, wherein the entire dislodgeable plug is fully dislodgeable as a single piece from the open first end of the stopper,
• wherein, when the mixing vial is disposed in the syringe and the plunger is axially moved, a force from the plunger causes the dislodgeable plug to be fully dislodged prior to the shoulder of the plunger contacting the closed second end of the stopper.