Dynamic bioactive nanofiber scaffolding
AssigneeMo-Sci Corporation
InventorsThomas E. Day, Steven B. Jung, Charanpreet S. Bagga
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Abstract
A resorbable bone graft scaffold material, including a plurality of overlapping and interlocking fibers defining a scaffold structure, plurality of pores distributed throughout the scaffold, and a plurality of glass microspheres distributed throughout the pores. The fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the fibers are a bioactive, resorbable material. The fibers generally contribute about 20 to about 40 weight percent of the scaffold material, with the microspheres contributing the balance.
Claims20
A resorbable tissue graft scaffold material, consisting essentially of:
- a plurality of overlapping and interlinking polymer-free, bioactive ceramic fibers defining a three-dimensional, flexible, porous scaffold;
- and
- a plurality of bioactive, resorbable glass or ceramic beads distributed throughout the porous scaffold;
- wherein the beads contribute from 60 weight percent to 95 weight percent of the tissue graft scaffold material and wherein the tissue graft scaffold is polymer-free.
Dependencies are inferred from the claim text.