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US 11,845,786 B2Granted
Peptides inhibiting KLK1, KLK4, or KLK4 and KLK8
AssigneeDaiichi Sankyo Company, Limited
InventorsDaisuke Nishimiya, Masakazu Tamura
Life of this patent
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Abstract
A novel peptide which comprises an amino acid sequence represented by SEQ ID NO: 23, and specifically inhibits the protease activity of a target molecule.
Claims23
A serine protease inhibitor kazal-type 2 (SPINK2) mutant peptide which comprises the amino acid sequence represented by SEQ ID NO:
- 9, SEQ ID NO:
- 10, SEQ ID NO:
- 11, or SEQ ID NO:
- 12.
1 more element
A serine protease inhibitor kazal-type 2 (SPINK2) mutant peptide which comprises the amino acid sequence represented by SEQ ID NO:
- 9, SEQ ID NO:
- 10, SEQ ID NO:
- 11, or SEQ ID NO:
- 12, and specifically inhibits protease activity of Kallikrein-related peptidase 4 (KLK4).
1 more element
A polynucleotide comprising a nucleotide sequence encoding the peptide sequence of SEQ ID NOs:
- 9-12.
Dependencies are inferred from the claim text.