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US 11,840,495 B2Granted
Compositions and methods related to di-substituted bicyclo[2.2.1] heptanamine-containing compounds
AssigneesThe Broad Institute, Inc., Instituto Carlos Slim De La Salud, A.C., The Brigham and Women's Hospital, Inc.
InventorsBrian T. Chamberlain, David Kornfilt, Florence F. Wagner, Maria Alimova, Anna Greka, Joseph Growney
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Abstract
The present disclosure relates to compositions and methods related to bicyclo[2.2.1] heptanamine-containing compounds and salts.
Claims16
A compound having a structure represented by formula IVo:
- or a stereoisomer or pharmaceutically acceptable salt thereof, wherein:
- R1A is ethyl and R1B is C1-6 alkyl, C2-6 alkenyl, or C2-6 alkynyl;
- or
- R1A is methyl and R1B is ethyl;
- wherein R1A and R1B are each independently and optionally substituted with 1, 2, 3, 4, 5, or 6 deuterium or halogen atoms;
- both instances of R3 are H or are C1-6 alkyl.
3 more elements
A compound selected from:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.