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AssigneeYale University
InventorsYung-Chi Cheng, Wing Lam, Zaoli Jiang
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In one embodiment, the present invention is directed to a composition comprising an aqueous or ethanolic extract of at least one herb selected from the group consisting of Aloe barbadensis (:F3), Rheum palmatum L. (:B6), Stephania tetrandra (:C4), Phellodendron chinense Schneid. (:D8), Euphorbia humifusa (:S6), Eclipta prostrata (:I2), A. venetum L. (:F1), Portulaca oleracea L. (:F5), and Sanguisorba officinalis L. (:E5), Camellia sinensis var. assamica (Mast.) Kitamura (:PE) and Punica granatum. (:PG), and mixtures thereof. The composition is administered to a patient, in an effective amount, in a method of treating, inhibiting, preventing, reducing the incidence of, ameliorating or resolving a disease state or condition caused in part or exacerbated by hyperactivity of the androgen receptor (AR), by inhibiting the androgen receptor protein. These compositions may also be used inhibit or stabilize hair loss or grow hair in a subject in need.
A method for treating, inhibiting, preventing, reducing the incidence of, ameliorating or resolving prostate cancer in a patient or subject in need comprising administering to said patient or subject a medicament comprising an effective amount of an extract of Euphorbia humifusa (S6) in combination with an effective amount of at least one extract selected from the group consisting of an extract of Apocynum venetum L. (F1), an extract of Aloe barbadensis (F3), an extract of Eclipta prostrata (I2) and an extract of Camellia sinensis var. assamica (Mast.) Kitamura (PE).
Dependencies are inferred from the claim text.