Back to results
US 11,834,480 B2Granted
Protein inhibitors with reduced immunogenicity and resistance to degradation, and methods for their preparation and use
AssigneeAmide Technologies
InventorsKyle Totaro, Travis Ness, Brady Summers, Bradley Pentelute
Life of this patent
Estimating the term…
Abstract
Methods are provided to identify therapeutically useful peptides and polypeptides that bind to HR1 and may be used to treat coronavirus infections. Polypeptides and pharmaceutical compositions useful for such purposes are described.
Claims17
A mirror-image polypeptide comprising the the amino acid sequence selected from the group consisting of ATVKFTYQGEEKQVDISKIKWVLRSGQRIWFSYDEGGGAWGYGWVSEKDAPKELL QMLEKQ (SEQ ID NO:
- 10) and
- ATVKFTYQGEEKQVDISKIKYVLRIGQAIWFRYDEGGGAIGNGWVSEKDAPKELLQ MLEKQ (SEQ ID NO:
- 12);
- wherein the mirror-image polypeptide is comprised of D-amino acids.
1 more element
Dependencies are inferred from the claim text.