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US 11,834,392 B2Granted
KDM4B inhibitors for the treatment of inflammatory diseases and disorders
AssigneeMUSC Foundation for Research Development
InventorsPatrick M. Woster, Joy E. Kirkpatrick
Life of this patent
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Abstract
The invention relates to KDM4B inhibitors, compositions comprising an effective amount of KDM4B inhibitors and methods for treating inflammatory diseases and disorders.
Claims22
A compound of Formula (I):
- wherein:
- R1 is hydrogen, lower alkyl or alkoxy;
- R2 is hydrogen, lower alkyl or alkoxy;
- R3 is hydrogen or —COOH;
- R4 is hydrogen, halogen or —COOH
- R5 is fluorine;
- R6 is hydrogen, halogen or lower alkyl;
- and
- R7 is hydrogen, halogen or lower alkyl;
- with the provisos that R1 and R2 are not both H;
- R3 and R7 are not both H;
- R5, R6 and R7 are not all F, or a pharmaceutically acceptable salt thereof.
9 more elements
Dependencies are inferred from the claim text.