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US 11,826,465 B2Granted
Nebulization formulations for delivery to lower respiratory tract
AssigneeCMPD Licensing, LLC
InventorJay Richard Ray, II
Life of this patent
Estimating the term…
Abstract
A method of making a pharmaceutical composition for delivery to the lower respiratory tract via nebulization within a sterile diluent includes mixing dry powder ingredients including a beta agonist or anticholinergic and one or more additional ingredients to formulate a dry powder mixture for mixing with the sterile diluent.
Claims24
A method of delivering a pharmaceutical composition to the lower respiratory tract, the method comprising:
- combining a dry powder with a sterile diluent to formulate a solution or suspension;
- and
- nebulizing the solution or suspension, wherein the dry powder comprises a beta agonist or an anticholinergic,
- wherein the sterile diluent is a sterile aqueous diluent, wherein the dry powder includes the beta agonist and the beta agonist is selected from levalbuterol or albuterol in a unit dose amount of about 0.5 mg to about 2.5 mg, wherein the dry powder further includes xylitol or poloxamers, and wherein the dry powder further includes a mucolytic comprising acetylcysteine in a unit dose amount of about 0.5 mg to about 100 mg.
1 more element
A method of delivering a pharmaceutical composition to the lower respiratory tract, the method comprising:
- combining a dry powder with a sterile diluent to formulate a solution or suspension;
- and
- nebulizing the solution or suspension, wherein the dry powder comprises a beta agonist or an anticholinergic,
- wherein the sterile diluent is a sterile aqueous diluent, wherein the dry powder includes the anticholinergic comprising ipratropium in a unit dose amount of about 0.1 mg to about 1.0 mg, wherein the dry powder further includes xylitol or poloxamers, and wherein the dry powder further includes a mucolytic comprising acetylcysteine in a unit dose amount of about 0.5 mg to about 100 mg.
1 more element
Dependencies are inferred from the claim text.