Coaxial nozzle configuration and methods thereof

A capsule fabrication system comprising:

• a coaxial nozzle comprising a core channel, an annular channel, and a sheath channel, the coaxial nozzle configured to form a compound flow of at least one fluid, wherein the annular channel and the sheath channel are configured to increase uniformity of velocity of distribution of fluid flow at an annular channel outlet and a sheath channel outlet of the coaxial nozzle,
• wherein the annular channel has a diameter of about 8.5 mm, a first length of between about 2.0 mm and about 4.0 mm, a second length of between about 12.5 mm and about 13.0 mm, and a height between about 2.0 mm and about 2.5 mm, and
• wherein the sheath channel has a length between about 1.5 mm and about 2.0 mm, a first diameter between about 14.0 mm and about 16.0 mm, a second diameter between about 11.0 mm and about 13.0 mm, and a height between about 8.0 mm and about 8.6 mm, the capsule fabrication system further comprising:
• a fluid delivery system configured to deliver a first fluid of the at least one fluid to the core channel, a second fluid of the at least one fluid to the annular channel, and a third fluid of the at least one fluid to the sheath channel, wherein the compound flow comprises at least one of:
• a core flow of the first fluid, an annular flow of the second fluid, and a sheath flow of the third fluid;
• a vibrator configured to introduce a vibration to the compound flow to form one or more capsules;
• and
• a collection bath configured to receive one or more capsules from the coaxial nozzle.