A filling device for a dosed filling of a liquid or fine powdery product from a product storage container into product dose receiving containers provided in a disposable isolator so as to be protected against contamination, the filling device comprising:
- the disposable isolator together with the product dose receiving containers provided therein;
- means for holding the product storage container together with contents of the product storage container outside of the disposable isolator;
- a controllable product removal device for a dosed removal of the product from the product storage container outside of the disposable isolator;
- a product dispensing device within the disposable isolator for the dosed dispensing of the product to the product dose receiving containers in the disposable isolator;
- a line assembly interconnecting the product storage container and the product dispensing device to conduct the product removed from the product storage container by means of the product removal device to the product dispensing device;
- at least one clamp-on-type ultrasonic flowmeter outside of the disposable isolator, on the line assembly, the flowmeter being fixed to an outside of the line assembly to surround at least some regions of the line assembly to detect a relevant flow rate;
- and
- a controller for measuring a relevant product dose to be removed from the product storage container on the basis of information from the flowmeter regarding the flow rate and for controlling the product removal device.