Production of steviol glycosides in recombinant hosts

A recombinant host cell capable of producing one or more steviol glycosides or a steviol glycoside composition in a cell culture, comprising:

• (a) a recombinant gene encoding a polypeptide capable of synthesizing uridine 5′-triphosphate (UTP) from uridine diphosphate (UDP);
• wherein the polypeptide comprises a polypeptide having at least 90% sequence identity to the amino acid sequence set forth in SEQ ID NO:123;
• (b) a recombinant gene encoding a polypeptide capable of converting glucose-6-phosphate to glucose-1-phosphate;
• wherein the polypeptide comprises a polypeptide having at least 90% sequence identity to the amino acid sequence set forth in any one of SEQ ID NOs:2, 119, 141, 143, 145, or 147;
• and/or
• (c) a recombinant gene encoding a polypeptide capable of synthesizing uridine diphosphate glucose (UDP-glucose) from UTP and glucose-1-phosphate;
• wherein the polypeptide comprises a polypeptide having at least 90% sequence identity to the amino acid sequence set forth in any one of SEQ ID NOs:121, 125, 127, 129, 131, 133, 135, 137, or 139.