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US 11,820,792 B2Granted
Cancer treatment
AssigneeImperial College Innovations Limited
InventorsAmin Hajitou, Keittisak Suwan, Mariam Albahrani, Sajee Waramit
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AssigneeImperial College Innovations Limited
InventorsAmin Hajitou, Keittisak Suwan, Mariam Albahrani, Sajee Waramit
Estimating the term…
The present invention provides phagemid vectors and associated phagemid particles for cancer treatment, and in particular, to the use of novel phagemid particles and associated expression systems for the treatment, prevention, amelioration, or management of cancer. In particular, the invention relates to the use of phagemid particles and expression systems for the delivery of transgenes encoding cytokines, for the treatment, prevention, amelioration, or management of cancer. The invention also extends to the use of phagemid particles and expression systems for the delivery of transgenes, and for the combination of such treatment with the use of adoptively transferred T cells, for the treatment, prevention, amelioration, or management of cancer.
A method of expressing one or more cytokines in a cell, the method comprising transducing the cell with a recombinant phagemid particle comprising M13 phage coat proteins and a phagemid particle genome that expresses a transgene expression cassette in the cell,
Dependencies are inferred from the claim text.