Use of glucocorticoids for the treatment of epithelial microbial infections of a fluid containing organ with a natural exterior orifice in mammals
AssigneeVirbac
InventorsBertrand Havrileck, Pierre Jasmin, David McGahie
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Abstract
The disclosure is directed to glucocorticoids for the treatment of epithelial microbial infections in fluid-containing organ having a natural exterior orifice in mammals; this new therapeutic use finds particular interest in the treatment of epithelial microbial infections of ear (such as otitis externa), udder (such as mastitis), and uterus (such as endometritis).
Claims17
A method for the treatment and/or the prevention of an epithelial microbial infection of the ear in a non-human mammal in need thereof, the method comprising topically administering in the ear to be treated an effective amount of hydrocortisone or a salt thereof to the non-human mammal, wherein said epithelial microbial infection is otitis externa,
- wherein the effective amount of hydrocortisone or its salt is between 0.1 and 0.5 mg and is administered at least once a week when said method is for prevention, and/or is administered once a day up to 20 consecutive days when said method is for treatment.
A method for the treatment and/or the prevention of an epithelial microbial infection of the ear in a non-human mammal in need thereof, the method comprising topically administering in the ear to be treated an effective amount of hydrocortisone or a salt thereof to the non-human mammal, wherein said epithelial microbial infection is otitis externa,
- wherein said hydrocortisone or a salt thereof is formulated in a pharmaceutical composition also comprising a pharmaceutically acceptable carrier and wherein said composition does not contain any antibiotic agent, antifungal agent, antiviral agent or antimicrobial agent.
Dependencies are inferred from the claim text.