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US 11,819,503 B2Granted
Method of treating coccidioides infection
AssigneesF2G Limited, Nathan P. Wiederhold, Thomas F. Patterson
InventorsDerek Law, John H. Rex, Michael Birch, Nathan P. Wiederhold, Thomas F. Patterson
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Abstract
The invention relates to the therapeutic use of olorofim, 2-(1,5-dimethyl-3-phenyl-1H-pyrrol-2-yl)-N-(4-(4-(5-fluoropyrimidin-2-yl)piperazin-1-yl)phenyl)-2-oxoacetamide in the prevention and treatment of a fungal infection caused by a Coccidioides species.
Claims13
A method of treating disseminated coccidioidomycosis in a subject, which method comprises:
- administering to said subject an effective amount of:
- 2-(1,5-dimethyl-3-phenyl-1H-pyrrol-2-yl)-N-(4-(4-(5-fluoropyrimidin-2-yl)piperazin-1-yl)phenyl)-2-oxoacetamide, or a pharmaceutically acceptable salt thereof, wherein the disseminated coccidioidomycosis is caused by a Coccidioides species selected from the group consisting of Coccidioides immitis, Coccidioides psoadasii and a combination thereof.
Dependencies are inferred from the claim text.