Peptides and methods and uses thereof for modulating anaphase promoting complex (APC) activity
AssigneeUniversity of Saskatchewan & National Research Council of Canada
InventorsTroy Harkness, Terra Gayle Arnason, Pankaj Bhowmik
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Abstract
Novel activators of the APC complex and methods and uses of these activators are provided. In particular, the activators are used for increasing resistance to stress and/or increasing lifespan in a plant or mammalian cell, in a plant or mammalian embryo or in a plant or subject. The activators are also used for treating cancer in a subject.
Claims15
A peptide comprising
- amino acid sequence GSSHNDARVRRLT (SEQ ID NO:
- 34),
- wherein the peptide has a maximum length of 30 amino acids.
A method of increasing resistance to stress and/or increasing lifespan in a plant, mammalian or microbial cell, in a plant or mammalian embryo or in a plant or subject, the method comprising administering a peptide comprising amino acid sequence GSSHNDARVRRLT (SEQ ID NO:
- 34) to the plant, mammalian or microbial cell, the plant or mammalian embryo or the plant or the subject, wherein the peptide has a maximum length of 30 amino acids.
Dependencies are inferred from the claim text.