US 11,814,333 B2 · Cationic lipids and transfection methods

Abstract

The present invention relates in part to novel cationic lipids and their use, e.g., in delivering nucleic acids to cells.

Dependent claims

A method for transfecting a cell with a nucleic acid, comprising contacting the cell with a nucleic acid and a compound of the formula:

Dependencies are inferred from the claim text.

Facts

Application

17/553,564Filed 16 Dec 2021 · continuation

Priority

30 Jul 2019

Published

US 2022/0106256 A17 Apr 2022

Granted

14 Nov 2023

Term ends

Not estimatedThe source records don’t support an estimate.

C07C 215/14
And acyclic: the nitrogen atom of the amino group being further bound to hydrocarbon groups substituted by amino groups
C07C 215/24
The carbon skeleton being unsaturated: and acyclic
A61K 9/0019
Galenical forms characterised by the site of application: injectable compositions; Intramuscular, intravenous, arterial, subcutaneous…
A61K 9/127
Dispersions; Emulsions: synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Family

Application16/526,621Parent of this continuation · filed 30 Jul 2019

Application16/660,317Parent of this continuation · filed 22 Oct 2019

US 10,501,404 B1Parent of this continuation · filed 10 Dec 2019

Application16/746,279Parent of this continuation · filed 17 Jan 2020

US 10,611,722 B1Parent of this continuation · filed 7 Apr 2020

Application16/930,901Parent of this continuation · filed 16 Jul 2020

US 10,752,576 B1Parent of this continuation · filed 25 Aug 2020

US 2022/0106256 A1Pre-grant publication · published 7 Apr 2022

US 11,242,311 B2Parent of this continuation

US 2021/0032192 A1Published application

US 11,814,333 B2This patent

From the US filing history. Foreign family members aren’t listed.