Epstein-Barr virus-like particles with broadened antigenic spectrum
AssigneeDeutsches Krebsforschungszentrum
InventorsHenri-Jacques Delecluse, Dwain Van Zyl
Life of this patent
Estimating the term…
Abstract
The present invention relates to a preparation comprising Epstein-Barr virus-like particles (EB-VLPs), said EB-VLPs being essentially free of Epstein Barr virus (EBV) DNA, wherein said EB-VLPs comprise a vaccination polypeptide comprising at least one peptide of an EBV tegument polypeptide and at least one immunogenic peptide; and to polynucleotides, host cells, and methods related thereto.
Claims15
A preparation comprising Epstein-Barr virus-like particles (EB-VLPs), said EB-VLPs being essentially free of Epstein Barr virus (EBV) DNA, wherein said EB-VLPs comprise a vaccination polypeptide, said vaccination polypeptide comprising at least one peptide of an EBV tegument polypeptide and at least one immunogenic peptide, wherein said at least one immunogenic peptide is an immunogenic peptide not derived from a tegument polypeptide of EBV, and wherein said at least one immunogenic peptide comprises at least one T-cell epitope.
Dependencies are inferred from the claim text.