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US 11,802,151 B2Granted
Brain-specific angiogenesis inhibitor 1 (BAI1) antibodies and uses thereof
AssigneeCode Biotherapeutics, Inc.
InventorsRobert Getts, Jessica Bowers, Mindy Ellen George-Weinstein, Jacquelyn Gerhart
Life of this patent
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Abstract
The present disclosure provides an antibody that binds human Adhesion G Protein-Coupled Receptor B1 (BAI1) protein, compositions comprising the same, and use thereof in methods of detection, methods of diagnosis, and methods of treatment.
Claims18
An antibody, or antigen-binding fragment thereof, that binds to human Adhesion G Protein-Coupled Receptor B1 (BAI1) protein, wherein the antibody, or antigen-binding fragment thereof, comprises:
- a first complementarity determining region (CDR) in the variable heavy (VH) chain (VH-CDR1) comprising an amino acid sequence according to SEQ ID NO:7;
- a second CDR in the VH chain (VH-CDR2) comprising an amino acid sequence according to SEQ ID NO:8;
- a third CDR in the VH chain (VH-CDR3) comprising an amino acid sequence according to SEQ ID NO:9;
- a first CDR in the variable light (VL) chain (VL-CDR1) comprising an amino acid sequence according to SEQ ID NO:10;
- a second CDR in the VL chain (VL-CDR2) comprising an amino acid sequence according to SEQ ID NO:11;
- and
- a third CDR in the VL chain (VL-CDR3) comprising an amino acid sequence according to SEQ ID NO:12.
4 more elements
Dependencies are inferred from the claim text.