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US 11,801,364 B2Granted
Electrospray catheter
AssigneeAvectas Limited
InventorsMichael Maguire, Shane Finnegan
Life of this patent
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Abstract
An apparatus includes a catheter, and an electrode and methods of delivering molecules to eukaryotic cells using such an apparatus. The catheter defines a fluidic channel and has a distal opening. The electrode is within the fluidic channel and is spaced a distance from the distal opening of the catheter. The catheter is arranged to prevent direct contact between any electrode of the apparatus and tissue. Related apparatus, systems, techniques and articles are also described.
Claims8
An apparatus comprising:
- a catheter defining a fluidic channel and having a distal opening, wherein the fluidic channel is configured to receive a metered volume of fluid, and wherein the fluid contains ethanol at greater than 5% concentration;
- an electrode within the fluidic channel and spaced a distance from the distal opening of the catheter;
- a porous tip disposed within the fluidic channel and disposed near the distal opening of the catheter, the porous tip comprising a material that is absorbent and fibrous, and wherein the porous tip is arranged in a cone shape geometry;
- a protrusion disposed near the distal opening of the catheter and surrounding an outer surface of the catheter;
- a thermoplastic wrap that encloses the protrusion to provide sealing and electrical isolation, such that the apparatus produces no current exceeding 100 μA;
- and
- a pump coupled to the catheter, wherein the pump is configured to provide the metered volume of fluid to the fluidic channel, wherein the metered volume of fluid is between 1 and 10 microliters of fluid per actuation of the pump,
- wherein the catheter is arranged to prevent direct contact between any electrode of the apparatus and tissue.
5 more elements
Dependencies are inferred from the claim text.