Antibody-drug conjugates including hemiasterlin derivative
AssigneeSumitomo Pharma Co., Ltd.
InventorsHitoshi Ban, Atsushi Suwa, Yosuke Takanashi
Life of this patent
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Abstract
A compound represented by formula (1-1): wherein b represents an integer of 1 to 5; and Z is a group represented by formula (Z-1), formula (Z-2), formula (Z-3), formula (Za-1), formula (Za-2), formula (Za-3), formula (Za-4) or formula (Za-5), or a salt thereof.
Claims24
A compound selected from the following compounds:
- or a salt thereof.
A compound below:
- or a salt thereof.
A compound below:
- or a salt thereof.
A compound below:
- or a salt thereof.
A compound below:
- or a salt thereof.
A compound below:
- or a salt thereof.
An antibody-drug conjugate selected from the following antibody-drug conjugates:
- wherein mAb represents an antibody and q represents an integer of 1 to 8,
- or a pharmaceutically acceptable salt thereof.
An antibody-drug conjugate below:
- wherein mAb represents an antibody and q represents an integer of 1 to 8,
- or a pharmaceutically acceptable salt thereof.
An antibody-drug conjugate below:
- wherein mAb represents an antibody and q represents an integer of 1 to 8,
- or a pharmaceutically acceptable salt thereof.
An antibody-drug conjugate below:
- wherein mAb represents an antibody and q represents an integer of 1 to 8,
- or a pharmaceutically acceptable salt thereof.
An antibody-drug conjugate below:
- wherein mAb represents an antibody and q represents an integer of 1 to 8,
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.