Venous blood flow stimulator for extracorporeal therapy

A blood filtration system, comprising:

• a blood flow stimulator for encouraging blood flow in a limb of a patient, including:
• a housing including a sealable volume, wherein the housing is configured to receive the limb of the patient within the sealable volume;
• a seal coupled with the housing and configured to engage with the limb to segregate the sealable volume from a surrounding environment of the blood flow stimulator;
• a conduit extending through the housing, wherein:
• the conduit provides access to the sealable volume from the surrounding environment;
• and
• the conduit is configured to receive a portion of a blood filtration circuit that is external of the patient;
• a force generator configured to generate a vacuum within the sealable volume and to generate a force upon skin of the limb to encourage blood flow in the limb when the limb is received in the sealable volume;
• and
• a controller including processing circuitry configured to operate the force generator to generate the force applied to the skin of the patient.