Solutions and dispersions of amide compounds
AssigneeFirmenich SA
InventorsPascal Beaussoubre, Wolfgang Fieber, Howard Munt
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Abstract
Provided herein is a process for increasing the dissolution rate of a sparingly water soluble flavor or taste modifying compound in water comprising: a. mixing the compound and a highly water soluble second compound in a water based solution to form a solution or dispersion of the compound; and b. drying the solution or dispersion to form a solution or solid dispersion of the compound wherein the compound has an increased dissolution rate in water as compared to the compound when dissolved in water alone.
Claims10
A process for increasing the dissolution rate of a sparingly water soluble compound, the method comprising:
- a. mixing a sparingly water soluble compound and a highly water soluble second compound in an aqueous composition to form a solution or dispersion of the sparingly water soluble compound;
- and
- b. drying the solution or dispersion to form a solid composition comprising the sparingly water soluble compound and the highly water soluble second compound;
- wherein the sparingly water soluble compound is a compound of Formula (I):
- Wherein
- n is an integer from 0 to 2;
- the dotted line represents a carbon-carbon single or double bond;
- and each of R1 to R4, when taken independently from each other, represents a hydrogen atom —OH, R5, or an OR5 group, wherein R5 represents a C1 to C5 alkyl group, and no more than one of R1 to R4 is —OH;
- or R1 and R2 or R3 and R4 combine, when substituting adjacent atoms of the phenyl group, to form an OCH2O group, provided said groups taken together substitute adjacent carbon atoms of the phenyl group;
- and
- wherein the highly water soluble second compound is selected from the group consisting of ribotides, amino acids, MSG, and mixtures thereof.
Dependencies are inferred from the claim text.