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US 11,786,601 B2Granted
Pegylated capsule-degrading enzyme for the treatment of anthrax
AssigneeThe Government of the United States of America, as represented by the Secretary of the Navy
InventorsPatricia M. Legler, Arthur M. Friedlander, Jaimee R. Compton
Life of this patent
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Abstract
A pegylated, circularly permuted construct of the CapD enzyme (a gamma glutamyl transferase enzyme acting as a hydrolase specific to poly-γ-D-glutamic acid) is used to treat anthrax and other bacterial infections, including but not limited to infection with strains that are resistant to available antibiotics.
Claims2
A pegylated protein comprising SEQ ID NO:
- 2, SEQ ID NO:
- 3, SEQ ID NO:
- 4, or SEQ ID NO:
- 5.
1 more element
A medicament comprising a pegylated protein comprising SEQ ID NO:
- 2, SEQ ID NO:
- 3, SEQ ID NO:
- 4, or SEQ ID NO:
- 5.
1 more element
Dependencies are inferred from the claim text.