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US 11,786,564 B2Granted
Probiotic immunomodulatory compositions
AssigneeUute Scientific Oy
InventorsAki Sinkkonen, Mira Grönroos, Heikki Hyöty, Olli-Heikki Laitinen, Noora Nurminen, Sami Oikarinen
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Abstract
The invention discloses an immunomodulatory composition comprising non-culturable bacteria, a method of production and an article and an apparatus for its use and administration.
Claims10
A food ingredient comprising a microbial community of non-culturable bacteria, wherein:
- i. the microbial diversity is at least 3 at Shannon diversity index;
- ii. the microbial richness is at least 130 operational taxonomic units;
- iii. the microbial abundance is at least 1,000,000 bacterial 16S copies g−1 ww;
- and
- the abundance of pathogens is below 500 16S gene sequences per 0.25 g sample in bacterial genera Acinetobacter, Actinomyces, Aerococcus, Aeromonas, Arcobacter, Bacillus, Bacteroides, Bifidobacterium, Brevibacillus, Brevundimonas, Chryseobacterium, Corynebacterium, Fibrobacter, Finegoldia, Gemella, Lactobacillus, Legionella, Leptotrichia, Moraxella, Mycobacterium, Myroides, Neisseria, Nocardia, Paenibacillus, Prevotella, Pseudomonas, Pseudonocardia, Psychrobacter, Rhodococcus, Rickettsia, Saccharomonospora, Sphingomonas, Stenotrophomonas, Streptococcus, and Treponema.
2 more elements
Dependencies are inferred from the claim text.