Back to results
US 11,779,910 B2Granted
Processes for isotopic modification of polyunsaturated fatty acids and derivatives thereof
AssigneeBioJiva LLC
InventorsDragoslav Vidovic, Mikhail S. Shchepinov
Life of this patent
Estimating the term…
Abstract
Disclosed herein are methods for preparing isotopically modified polyunsaturated lipids containing 1,4-diene systems involving selective isotopic modification of one or more bis-allylic positions of the polyunsaturated lipids in the presence of a transition metal catalyst.
Claims13
A ruthenium complex of the formula I:
- wherein R and R′ comprise the remainder of linolenic acid, arachidonic acid, eicosapentaenoic acid, or docosahexaenoic acid or an ester thereof;
- wherein when present, the ester is a C1-C21 alkyl ester;
- wherein the ruthenium complex further comprises a cyclopentadiene (Cp) ligand;
- and
- wherein ruthenium in the ruthenium complex is in the +1 oxidation state (Ru+1).
2 more elements
Dependencies are inferred from the claim text.