Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals
AssigneeThe Government of the United States of America, as represented by the Secretary of the Navy
InventorsR. Andrew McGill, Courtney A. Roberts
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Abstract
The invention relates to strong hydrogen-bond acidic sorbents. The sorbents may be provided in a form that limits or eliminates intramolecular bonding of the hydrogen-bond acidic site between neighboring sorbent molecules, for example, by providing steric groups adjacent to the hydrogen-bond acidic site. The hydrogen bond site may be a phenolic structure based on a bisphenol architecture. The sorbents of the invention may be used in methods for trapping or detecting hazardous chemicals or explosives.
Claims6
A method for collecting an analyte comprising one or more hydrogen-bond basic groups, the method comprising:
- providing a layer of a bisphenol sorbent comprising a compound of formula I or formula II as a chromatographic stationary phase
- wherein
- R1 is selected from the group consisting of prop-1-en-2-yl;-dimethyl(phenyl)silyl;
- trimethylsilyl;
- diphenylmethyl;
- methylthio;
- prop-2-enyl;
- benzyl;
- ethylthio;
- cyclopropyl;
- 2-(trimethylsilyl)ethyl;
- 2,2-dimethylpropyl;
- 2-methylpropyl;
- phenylethyl;
- propyl;
- butyl;
- sec-butyl;
- pentyl;
- heptyl;
- propan-2-yl;
- cyclopentyl;
- cyclohexyl;
- cyclobutyl;
- 3-ethylpentan-3-yl;
- ethyl;
- 1,1-dimethylpropyl;
- (trimethylsilyl)methyl;
- trifluoromethyl;
- and fluoro;
- and
- R2 is selected from the group consisting of methyl;
- tert-butyl;
- prop-1-en-2-yl;
- dimethyl(phenyl)silyl;
- trimethylsilyl;
- diphenylmethyl;
- methylthio;
- prop-2-enyl;
- benzyl;
- ethylthio;
- cyclopropyl;
- 2-(trimethylsilyl)ethyl;
- 2,2-dimethylpropyl;
- 2-methylpropyl;
- phenylethyl;
- propyl;
- butyl;
- sec-butyl;
- pentyl;
- heptyl;
- propan-2-yl;
- cyclopentyl;
- cyclobutyl;
- 3-ethylpentan-3-yl;
- ethyl;
- 1,1-dimethylpropyl;
- (trimethylsilyl)methyl;
- trifluoromethyl;
- and fluoro;
- and
- contacting the bisphenol sorbent with a sample comprising the analyte, thereby collecting the analyte,
- wherein the bisphenol selectively binds with the stronger hydrogen-bond basic analyte as compared to weaker hydrogen-bond basic interferents, forming bisphenol sorbent-analyte bonds.
Dependencies are inferred from the claim text.