# US 11,779,770 B2 · Universal pacing of a catheter > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,779,770 B2 - Document ID: US11779770B2 - Status: Granted - Kind: B2 - Application number: 16/938,200 - Filed: 2020-07-24 - Published: 2022-01-27 - Granted: 2023-10-10 - Earliest claimed: 2020-07-24 - Assignees: Biosense Webster (Israel) Ltd. - Applicants: Biosense Webster (Israel) Ltd. - Inventors: Lior Botzer - Web page: https://patentgrep.com/patent/US11779770B2 ## CPC - A61B 18/1492: {having a flexible, catheter-like structure, e.g. for heart ablation (A61B18/1477 takes precedence)} - A61N 1/3706: {Pacemaker parameters (stimulation threshold A61N1/371)} - A61B 5/361: Detecting fibrillation - A61B 5/363: Detecting tachycardia or bradycardia - A61B 5/6859: {with multiple distal splines} - A61M 25/0012: {with embedded structures, e.g. coils, braids, meshes, strands or radiopaque coils} - A61M 25/10: Balloon catheters ({A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02;} inflatable balloons for placing stents or stent-grafts A61F2/958 {; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00}) - A61N 1/056: {Transvascular endocardial electrode systems} - A61N 1/3702: {Physiological parameters (A61N1/365 takes precedence; evoked response A61N1/371)} - A61N 1/3716: {with reduction of residual polarisation effects} - A61B 2018/00357: {Endocardium} - A61B 2018/00839: {Bioelectrical parameters, e.g. ECG, EEG} - A61M 2210/125: Heart - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A method is provided. The method includes pacing, by electrodes of a catheter, a heart tissue with pulses. The method includes observing, by the electrodes, a period of electrophysiological repolarization for the heart tissue. The period of electrophysiological repolarization is caused by the pacing. The method also includes measuring, by the electrodes, an electrical signal within the heart tissue after the period of electrophysiological repolarization. ## Claims ### Claim 1 A method comprising: pacing, by a plurality of electrodes of a catheter, a heart tissue with a plurality of pulses; detecting, by the plurality of electrodes of the catheter, a period of electrophysiological repolarization for the heart tissue caused by the pacing; measuring, by the plurality of electrodes of the catheter, an electrical signal within the heart tissue after the period of electrophysiological repolarization; and measuring, by the plurality of electrodes of the catheter, an activity pattern of returning electrical signals after the electrical signal is measured in the heart tissue, the returning electrical signals propagating from the heart tissue. ### Claim 2 (depends on 1) The method of claim 1, wherein each electrode of the plurality of electrodes provides a pulse of the plurality of pulses. ### Claim 3 (depends on 1) The method of claim 1, wherein the period of electrophysiological repolarization comprises a time period when the heart tissue is in a refractory period. ### Claim 4 (depends on 1) The method of claim 1, further comprising: isolating and analyzing focal points of interest within the heart tissue based on the activity pattern across the plurality of electrodes. ### Claim 5 (depends on 1) The method of claim 1, wherein the catheter comprises a mesh, balloon, or spoon catheter. ### Claim 6 (depends on 1) The method of claim 1, wherein the plurality of electrodes comprises at least forty electrodes. ### Claim 7 (depends on 1) The method of claim 1, wherein each pulse of the plurality of pulses are paced together and at a same time. ### Claim 8 (depends on 1) The method of claim 1, wherein the plurality of pulses are paced to control a time between each pacing. ### Claim 9 (depends on 1) The method of claim 1, wherein each of a number or a location of the plurality of pulses is varied to manipulate the period of electrophysiological repolarization. ### Claim 10 (depends on 1) The method of claim 1, wherein an isolated section of the heart tissue is paced. ### Claim 11 An apparatus comprising: a catheter comprising a plurality of electrodes; and a cardiac pacing and diagnosis device comprising a memory storing processor executable instructions of cardiac pacing and diagnosis software, and a processor configured to execute the processor executable instructions of the cardiac pacing and diagnosis software to cause the apparatus to: pace, by the plurality of electrodes of the catheter, a heart tissue with a plurality of pulses; detect, by the plurality of electrodes of the catheter, a period of electrophysiological repolarization for the heart tissue caused by the pacing; measure, by the plurality of electrodes of the catheter, an electrical signal within the heart tissue after the period of electrophysiological repolarization; and measure, by the plurality of electrodes of the catheter, an activity pattern of returning electrical signals after the electrical signal is measured in the heart tissue, the returning electrical signals propagating from the heart tissue. ### Claim 12 (depends on 11) The apparatus of claim 11, wherein each electrode of the plurality of electrodes provides a pulse of the plurality of pulses. ### Claim 13 (depends on 11) The apparatus of claim 11, wherein the period of electrophysiological repolarization comprises a time period when the heart tissue is in a refractory period. ### Claim 14 (depends on 11) The apparatus of claim 11, wherein the processor is configured to execute the processor executable instructions of the cardiac pacing and diagnosis software to cause the apparatus to: isolate and analyze focal points of interest within the heart tissue based on the activity pattern across the plurality of electrodes. ### Claim 15 (depends on 11) The apparatus of claim 11, wherein the catheter comprises a mesh, balloon, or spoon catheter. ### Claim 16 (depends on 11) The apparatus of claim 11, wherein the plurality of electrodes comprises at least forty electrodes. ### Claim 17 (depends on 11) The apparatus of claim 11, wherein each of the plurality of pulses are paced together and at the same time. ### Claim 18 (depends on 11) The apparatus of claim 11, wherein the plurality of pulses are paced to control a time between each pacing.