Coating for medical devices
AssigneePhenox GmbH
InventorsUwe Schedler, Christian Heise, Thomas Thiele, Hans Henkes, Hermann Monstadt, Ralf Hannes, Tim Lenz-Habijan, Catrin Bannewitz
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Abstract
A medical device substrate with a coating including a functional layer located on the substrate, with the functional layer including at least one sugar alcohol and being bonded to the substrate directly or indirectly via a functionalization of the sugar alcohol. Alternatively, the functional layer may also include other saccharides, in which case it is essential that polymerization of the saccharides takes place only upon bonding to the substrate. The inventive medical device exhibits reduced platelet adhesion and aggregation.
Claims14
A medical device comprising a substrate provided with a coating, wherein the coating comprises a functional layer and the functional layer comprises an oligomer or polymer made from a monosaccharide, characterized in that,
- the monosaccharide from which the oligomer or polymer is made is linked directly or indirectly to the substrate via a functionalization of the monosaccharide and wherein the monosaccharide is oligomerized or polymerized only upon bonding of the monosaccharide to the substrate, wherein the monosaccharide in its non-functionalized form prior to oligomerization or polymerization comprises a sugar alcohol or a cyclic or heterocyclic compound that can be derived therefrom by dehydration.
Dependencies are inferred from the claim text.