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US 11,779,683 B2Granted
Extended release immunomodulatory implant to facilitate bone morphogenesis
OwnerLoubert S. Suddabyinventor
Life of this patent
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Abstract
An extended release immunomodulatory implant operatively arranged to facilitate bone morphogenesis, including an inner portion including at least one growth factor, a first layer including at least one of one or more interleukins and capsaicin, and a second layer including an antigen operatively arranged to activate an innate immune system.
Claims27
An extended release immunomodulatory implant operatively arranged to facilitate bone morphogenesis, comprising:
- an inner portion including at least one growth factor;
- a first layer arranged on the inner portion and including at least one of one or more interleukins and capsaicin;
- and,
- a second layer arranged on the first layer and including an antigen operatively arranged to activate an innate immune system, the second layer being at least partially phagocytosable.
1 more element
An extended release immunomodulatory implant operatively arranged to facilitate bone morphogenesis, comprising:
- an implant matrix including a first material, the implant matrix including:
- an inner portion including at least one of a concentrated growth factor (CGF) and a vascular endothelial growth factor (VEGF);
- a first layer arranged radially outward of the inner portion and including one or more interleukins;
- and,
- a second layer arranged radially outward of the first layer and including an antigen operatively arranged to activate the innate immune system.
2 more elements
Dependencies are inferred from the claim text.