Immunopotentiator, immunotherapeutic pharmaceutical composition and its preparation and use
AssigneeFudan University
InventorsBin Wang, Weidong Zhao, Gan Zhao, Yiwei Zhong
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Abstract
An immune enhancer comprising at least an interferon and a granulocyte-macrophage colony-stimulating factor, and an immunotherapeutic phar-maceutical composition comprising at least an antigen and the above-mentioned immune enhancers is disclosed. A preparation method of the immunotherapeutic pharmaceutical composition, the use of the immune enhancer and the immunotherapeutic pharmaceutical composition are also disclosed. The immune enhancer can be applied to disease and tumor treatments caused by viruses, bacteria, and other microorganisms.
Claims25
An immunotherapeutic pharmaceutical composition comprises at least an antigen and an immune enhancer, wherein the immune enhancer comprises at least a recombinant interferon and a granulocyte-macrophage colony-stimulating factor, wherein the ratio of the content of the recombinant interferon to the content of the recombinant granulocyte- macrophage colony-stimulating factor is (about 0.5×104 IU-about 5×104 IU) to (about 5 μg-about 50 μg), and the recombinant interferon is interferon alpha.
Dependencies are inferred from the claim text.