Method and system for selecting a region of interest in an image

A system for analysing or monitoring a subject, the system comprising:

• an object and landmark identifier configured to identify one or more objects of interest that have been segmented from a first image comprising any of a baseline scan, a follow-up scan or a reference image of the subject, and to identify predefined landmarks of the objects;
• a morphometer configured to determine reference morphometries pertaining to the objects by performing morphometrics on the objects by reference to the landmarks, wherein determining the reference morphometries includes applying one or more image processing algorithms to the first image to calculate basic morphometries;
• and
• a region selector configured to select one or more regions of interest (ROIs) from the objects according to the reference morphometries, comprising identifying respective locations of the ROIs and determining respective shapes and sizes of the ROIs relative to the reference morphometries;
• wherein the system is configured to:
• perform a first analysis of the one or more ROIs;
• perform at least one corresponding second analysis of the one or more ROIs in respectively at least one second image comprising any other of a baseline scan, a follow-up scan or a reference image;
• generate a comparison of one or more results of the first analysis and one or more corresponding results of the second analysis;
• and
• output the comparison.