Systems and methods for intra-procedure image-based flow quantification

A system for assessing efficacy of a vascular implant device that has been implanted in a particular position in a subject comprising:

• a computer system configured to:
• i) access image data acquired from a subject using a medical imaging system, wherein the image data includes at least one image of the vascular implant device implanted within the subject at a time after the subject has received an injection of a contrast agent at a contrast injection site;
• ii) determine, from the image data, a region of interest (ROI) downstream of the contrast injection site;
• iii) develop a contrast model from the image data;
• iv) use the contrast model to calculate a flow time constant;
• v) generate a report indicating an efficacy of the vascular implant device in the particular position in the subject using the flow time constant;
• and
• a display configured to display the report.

A method for supporting a clinical decision by characterizing flow within a subject's vasculature, comprising:

• accessing, with a computer system, image data acquired from a subject using a medical imaging system, wherein the image data include at least one image of a vasculature of the subject at a time after the subject has received an injection of a contrast agent at a contrast injection site;
• determining, from the image data, a region of interest (ROI) downstream of the contrast injection site;
• extracting, using the image data, voxel intensity values for the ROI over time;
• fitting the voxel intensity values to a contrast model;
• calculating a flow time constant using the contrast model;
• and
• generating a report indicating efficacy of flow through the vasculature.