Method and use of Radix puerariae polysaccharide in promoting lipid-lowering activity

A method of using Radix Puerariae polysaccharide QL to promote lipid-lowering activity in a subject, comprising:

• preparing a therapeutically effective dosage of a Radix Puerariae polysaccharide QL;
• wherein, the Radix Puerariae polysaccharide QL is a homopolysaccharide composed of one monosaccharide glucose, and has a molecular weight of 10 KDa to 60 KDa, a protein content of 0.64%, no glycuronic acid, and a sugar content of 98.7%;
• wherein, an infrared spectrum (IR) of the Radix Puerariae polysaccharide QL shows typical polysaccharide absorption peaks comprising a hydroxyl absorption peak around 3,300 cm−1, and a glycosyl absorption peak around 957 cm−1, but shows no carbonyl absorption peak at 1,700 cm−1, the IR of the Radix Puerariae polysaccharide QL is consistent with a measured glycuronic acid content;
• wherein, gas chromatography-mass spectrometry (GC-MS) analysis confirms that the Radix Puerariae polysaccharide QL is composed of glucose, wherein most glucose units are linked through α-1,3-Glu and a small number of glucose units are linked through terminal-Glu;
• and wherein, an atomic force microscopy (AFM) test shows that a spatial structure of the Radix Puerariae polysaccharide QL has a spherical characteristic;
• administering the therapeutically effective dosage of a Radix Puerariae polysaccharide QL in vivo to the subject at a dosage between 25 mg/kg and 100 mg/kg.