Back to results
US 11,767,357 B2Granted
Biological therapeutics for infection-relating disorders or conditions
AssigneeB&H Biotechnologies, LLC
InventorHuiru Wang
Life of this patent
Estimating the term…
Abstract
The present invention discloses products and the methods of uses of the products for preventing and treating infectious diseases and the disorders or conditions inducible by harmful antibodies. The harmful antibodies are induced during infection, or vaccination, or use of therapeutic antibodies. The products of the present disclosure comprise immunoglobulin products, serum or plasma, specific antibodies to viral pathogens.
Claims8
A therapeutic product for treating a patient infected by an influenza virus, comprising:
- (a) an effective amount of N-acetylneuraminic acid;
- (b) an effective amount of N-acetylneuraminic acid methyl ester;
- and
- (c) at least one of serum or plasma,
- wherein combination of the effective amount of N-acetylneuraminic acid and the effective amount of N-acetylneuraminic acid methyl ester with at least one of serum or plasma reduces a rate of death caused by the influenza virus by at least about 70% compared to treatment with the at least one of serum or plasma alone,
- wherein the effective amount of N-acetylneuraminic acid comprises about 0.1 mg/kg to about 100 mg/kg of N-acetylneuraminic acid per kg body weight of a subject,
- wherein the effective amount of N-acetylneuraminic acid methyl ester comprises about 0.1 mg/kg to about 100 mg/kg of N-acetylneuraminic acid methyl ester per kg body weight of a subject, and
- wherein the serum or plasma is obtained from a healthy individual.
5 more elements
Dependencies are inferred from the claim text.