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US 11,767,343 B2Granted
Peptide probe for recognition of G-quadruplex and use thereof in detection of G-quadruplex in cell
AssigneeChangzhi Medical College
InventorsZheng Tan, Kewei Zheng, Jinping Zheng
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Abstract
A polypeptide probe for detecting G-quadruplexes (G4s), includes: from two to four G4-binding domains, and one or more linkers disposed between every two G4-binding domains. Each G4-binding domain includes a specific motif including a sequence of amino acids PGHLKGREIGMWY (SEQ ID NO: 1).
Claims11
A polypeptide probe, comprising:
- from two to four G4-binding domains, and one or more linkers disposed between every two G4-binding domains;
- each G4-binding domain comprising a specific motif comprising a sequence of amino acids PGHLKGREIGMWY (SEQ ID NO:
- 1).
Dependencies are inferred from the claim text.